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BENIGN LYMPHOEPITHELIAL LES10N ARISING IN THE PAROTID GLAND

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Abstract

ÀúÀÚµéÀº ¾ç¼º ¸²ÇÁ»óÇǼº º´¼Ò·Î Áø´ÜµÈ 33¼¼ ¿©ÀÚȯÀÚ¿¡¼­ ÀÓ»ó ¡¤¹æ»ç¼±ÇÐÀû ¹× º´¸®
ÇÐÀûÀ¸·Î ´ÙÀ½°ú °°Àº ¼Ò°ßÀ» °üÂûÇÏ¿´´Ù.
1. ÀÓ»óÀûÀ¸·Î ȯÀÚ´Â ¾çÃø ÀÌÇϼ±ÀÇ ¹«Å뼺 Á¾Ã¢ ¹× ±¸°³ºÎÀÇ °ÇÁ¶ÁõÀ» È£¼ÒÇÏ¿´À¸¸ç Ç÷
û °Ë»ç¿¡¼­ rheumatoid factor°¡ °ËÃâµÇ¾ú´Ù.
2. Ÿ¾×¼±Á¶¿µ»ó¿¡¼­ ÀÌÇϼ±¿¡¼­ Ÿ¾×¼± Àüü¿¡ ±ÕÀÏÇÏ°Ô ºÐÆ÷µÇ¾î ÀÖ´Â ´Ù¼öÀÇ Á¡»ó ¶Ç
´Â ±¸»ó(punctate or globular)À¸·Î Á¶¿µÁ¦°¡ ¹¶ÃÄ ¼ÒÀ§ 'cherry blossom' ¶Ç´Â 'leafless
fruit-laden tree'ÀÇ ¸ð½ÀÀ» º¸¿´´Ù
3. Ÿ¾×¼± ½ºÄµ»ó¿¡¼­´Â ÀÌÇϼ±¿¡¼­ ¹æ»ç¼ºÇÙÁ¾ÀÇ ¼·Ã븦 °üÂûÇÒ ¼ö ¾ø¾ú´Ù.
4. ºÎºñµ¿ ÀÚ±â°ø¸í ¿µ»ó(PNS NRI)¿¡¼­ 71°­Á¶ ¿µ»ó¿¡¼­´Â ÀÌ Çϼ±°ú ºñ½ÁÇÑ Á¤µµÀÇ ½Å
È£°­µµ¸¦ º¸À̸ç T2°­Á¶¿µ»ó¿¡¼­´Â ÁÂÃø°ú ¿ìÃø ÀÌ Çϼ± ³»¿¡ °¢°¢ 1.3§¯, 2.1§¯ Å©±âÀÇ °í
½ÅÈ£°­µµ¸¦ º¸ÀÌ´Â º´¼Ò°¡ °üÂûµÇ¾ú´Ù.
5. ÃÊÀ½ÆÄ ¿µ»ó¿¡¼­´Â ÁÂÃø ÀÌÇϼ± ÇϹæºÎ¿¡ ¾à 20¡¿15§®, 17¡¿14§®Á¤µµÀÇ º´¼Ò°¡, ¿ìÃø
ÀÌÇϼ±ÀÇ ÇϹæºÎ¿¡¼­´Â ¾à 15¡¿11§® Å©±âÀÇ º´¼Ò°¡ Àú¿¡ÄÚ¼ºÀ¸·Î ³ªÅ¸³µÀ¸¸ç ±× ¿Ü¿¡µµ ¿©
·¯ °³ÀÇ ÀÛÀº Àú¿¡ÄÚ¼º º´¼Ò°¡ °üÂûµÇ¾ú´Ù.
6.Á¶Á÷º´¸®ÇÐÀû ¼Ò°ß¿¡¼­ Á¤»ó ¼±Á¶Á÷À» ´ëüÇÏ°í ÀÖ´Â ¸²ÇÁ±¸ ħÀ±°ú ¹èÁß½É(germinal
center)À» Çü¼ºÇÏ°í ÀÖ´Â ¸²ÇÁ¿©Æ÷(Iymphoid follicle)¸¦ °üÂûÇÒ ¼ö ÀÖ¾ú°í, »óÇDZٻóÇǵµ
(epimyoepithelial islands)°¡ º´ ¼Ò¿¡ »êÀçµÇ¾î ÀÖ¾úÀ¸¸ç ¾ç¼º ¸²ÇÁ»óÇǼº ³¶(benign Iym-
phoepithelial cyst)µµ °üÂûµÇ¾ú´Ù.
#ÃÊ·Ï#
The authors diagnosed a 33 years old female as benign Iymphoepithelial lesion after
undergoing clinical, radiological and histopathological examinations and the characteristics
were as follows :
1. Clinically, the patient complained of painless bilateral swelling of the parotid glands
and dryness of the palate. rheumatoid factor was detected in her serum.
2. Sialograms showed punctate or globular collections of contrast media distributed
evenly throughout the parotid glands in so-called 'cherry blossom' or 'leafless
fruit-laden tree' appearance.
3. A salivary gland scan showed no uptake of radioisotopes by the parotid glands.
4. At 71-weighted imaging of PNS MRI, the lesions had the same signal intensity as
the rest of the gland. At T2-weighted imaging, the lesions could be seen as high signal
intensity 1.3 cm and 2.1 cm in diameter in the left and the right parotid gland
respectively.
5. ultrasonogram showed sonolucent lesions 20¡¿15§® and 17¡¿14§® in size in the
lower part of the left parotid gland and another 18¡¿11§® in size in the lower part of
the carotid gland as well as many other small sonolucent lesions.
6. Histopathologically, Iymphocytic infiltration replacing the normal acini and Iymphoid
follicles containing germinal centers could be seen. Epimyoepithelial islands were
scattered throughout the lesion and benign Iymphoepithelial cysts were also observed.

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